In recent years, new portfolio construction techniques focused on risk and diversification rather than expected average returns have become quite popular. This success has been due to an increasing acknowledgment that a traditional balanced portfolio, where 60 percent is allocated in equities and the remaining 40 percent is invested in bonds, is not diversified at all. It may look balanced from a capital allocation point of view, but it is not from a risk perspective, as equities are the main risk contributor within such a portfolio. Therefore we would like to review a portfolio construction technique, called “Maximum Diversification”, which has shown incredible results so far. (A similar portfolio, the WSC All Weather Portfolio" is being updated on a regular basis on our website.)
Top 5 Net Payout Yield Companies To Invest In Right Now: Chelsea Therapeutics International Ltd.(CHTP)
Chelsea Therapeutics International, Ltd., a development-stage pharmaceutical company, focuses on the acquisition, development, and commercialization of therapeutic products for the treatment of various human diseases. It is involved in developing Droxidopa, a therapeutic agent for the treatment of symptomatic neurogenic orthostatic hypotension (NOH) associated with primary autonomic failure and falls related to NOH in Parkinson?s Disease (PD), as well as other norepinephrine-related conditions and diseases, including intradialytic hypotension, fibromyalgia, adult attention deficit hyperactivity disorder, chronic fatigue syndrome, and freezing of gait in PD and down syndrome. The company intends to market its Droxidopa drug under the Northera brand name. It also engages in developing a portfolio of molecules for the treatment of various autoimmune/inflammatory diseases, including rheumatoid arthritis, psoriasis, Crohn?s disease, ankylosing spondylitis, uveitis, psoriatic arthritis, inflammatory bowel disease, cancer, and other immunological disorders. The company?s molecule products include a portfolio of metabolically inert antifolate molecules consisting of CH-1504 and CH-4051, which are orally available molecules with anti-inflammatory, autoimmune, and anti-tumor properties that inhibit various key enzymes required for cell proliferation; and a portfolio of dihydroorotate dehydrogenase, known as the I-3D portfolio, for applications in autoimmune diseases and transplantation. Chelsea Therapeutics International, Ltd. was founded in 2002 and is headquartered in Charlotte, North Carolina.
Advisors' Opinion:- [By Jon C. Ogg]
Chelsea Therapeutics International Ltd. (NASDAQ: CHTP) is finding a serious victory from its hypotension drug. Shares hit a 52-week high — make that a three-year high — after the company confirmed an accelerated FDA approval of its Northera for the treatment of low blood pressure, following FDA panel backing just last month.
- [By MONEYMORNING]
The FDA is scheduled to make a decision on Chelsea's drug, Northera, on Feb. 14.
Chelsea's (CHTP) Northera DrugNorthera is used to treat patients with neurogenic orthostatic hypotension (nOH), a rare, lingering type of low blood pressure. nOH typically occurs upon standing and is commonly experienced by those with certain neurological disorders, including Parkinson's disease. Nearly 300,000 patients presently suffer from nOH in the U.S. and EU combined.
- [By John Udovich]
The biotech roller-coaster continues for investors into 2014 with small cap Chelsea Therapeutics International Ltd (NASDAQ: CHTP) set to more than double when the market opens today, meaning its time to take a closer look at what in the world is going on with the stocks plus take a closer look at the performance of biotech peers like the iShares NASDAQ Biotechnology Index ETF (NASDAQ: IBB) and SPDR S&P Biotech ETF (NYSEARCA: XBI).
- [By MONEYMORNING]
Chelsea Therapeutics International Ltd. (Nasdaq: CHTP) is a 10-year-old development-stage biopharmaceutical company headquartered in Charlotte, N.C. Shares got our attention mid-month when the stock soared 160% on heavy volume after a panel of federal experts recommended approval of its most advanced candidate, Northera. A blood pressure treatment designed to prevent dizziness and fainting in Parkinson's disease patients, the advisory group concluded the drug is effective enough to warrant regulatory approval. The outside panel's endorsement came with the condition the drug only be approved for short-term use in a defined group of patients.
Best Gas Utility Companies To Own For 2014: Shionogi & Co Ltd (SGIOF.PK)
Shionogi & Co., Ltd. is a Japan-based pharmaceutical company. It is engaged in the research, development, purchase, manufacture and sale of pharmaceuticals, as well as pharmaceutical-related businesses. The Company mainly provides vitamin preparations, analgesic antipyretics, eye care products, cold and sinus medicine, digestive medicine, dermatologic preparations, antiphlogistic analgetics, antihypercholesterolemic agents, test paper for glucose in urine and artificial teeth-related products. As of March 31, 2013, the Company had 32 consolidated subsidiaries and six associated companies. Advisors' Opinion:- [By Jason Melehani]
ViiV Healthcare, a collaborative HIV focused venture established by GlaxoSmithKline (GSK), Pfizer (PFE) and Shionogi & Co (SGIOF.PK), is seeking approval from the FDA and the European Union for dolutegravir, an integrase inhibitor used for the treatment of HIV. Integrase inhibitors act by preventing the reverse transcribed viral DNA from integrating into the human T cell DNA.
Best Gas Utility Companies To Own For 2014: ResMed Inc (RMD)
ResMed Inc., (ResMed), incorporated on March 31, 1994, is a holding company for the ResMed Group. The Company, through its subsidiaries, is a developer, manufacturer and distributor of medical equipment for treating, diagnosing, and managing sleep-disordered breathing and other respiratory disorders. Sleep-disordered breathing (SDB) includes obstructive sleep apnea (OSA), and other respiratory disorders that occur during sleep. The Company has developed a number of products for SDB and other respiratory disorders including airflow generators, diagnostic products, mask systems, headgear and other accessories. Its manufacturing operations are located in Australia, Singapore, France, Germany, Malaysia and the United States. Its distribution and sales sites are located in the United States, Germany, France, the United Kingdom, Switzerland, Australia, Japan, Norway and Sweden. In December 2013, ResMed Inc acquired Unimedis SRO, a surgical appliance and manufacturing company.
Air Flow Generators
The Company produces continuous positive airway pressure (CPAP), variable positive airway pressure (VPAP) and AutoSet systems for the titration and treatment of SDB. The flow generator systems deliver positive airway pressure through a patient interface, either a small nasal mask, nasal pillows system, or full-face mask. Its VPAP units deliver bilevel therapy. There are two preset pressures: a higher pressure as the patient breathes in, and a lower pressure as the patient breathes out. AutoSet systems are based on a technology to monitor breathing and can also be used in the diagnosis, treatment and management of OSA. The Company�� Stellar 100 and 150 ventilation devices, provide both invasive and non invasive ventilation applications for adult and pediatric patients.
ResMed Inc.�� CPAP products include S8 Escape, S9 Elite and S9 Escape. Its VPAP products include VPAP III STA with QuickNav, VPAP S / VPAP IV, VPAP IV ST, S8 Auto 25, VPAP Tx Lab System, S9 VPAP S, S9 VPAP ST! , S9 VPAP Auto, S9 VPAP Adapt, S9 AutoSet CS, S9 Auto 25 and S9 VPAP COPD. The Company�� automatic positive airway pressure products include S9 AutoSet and S9 Escape Auto. Its ventilation products include Elisee 150, VS III and Stellar 100 and 150.
Masks, Accessories, Motors and Diagnostic Products
Masks, accessories, motors and diagnostic products together accounted for approximately 46% of its net revenues in fiscal 2012. Its Mask products include Activa LT, Swift LT for Her, Swift FX, Mirage SoftGel, Quattro FX, Swift FX for Her, Mirage FX, Mirage FX for Her, Pixi Pediatric Mask, Quattro FX for Her, Swift FX Bella, Quattro Air and Swift FX Nano. Its diagnostic products includes ApneaLink + Oximetry and ApneaLink Plus (U.S.)
Accessories and Other Products
The Company to assist those professionals diagnosing or managing the treatment of patients have data communications and control products, such as the EasyCare, ResLink, ResControl, ResControl II, TxControl, ResScan and ResTraxx modules that facilitate the transfer of data and other information to and from the flow generators. These products include humidifiers, such as H5i and H4i, which connect directly with the CPAP, VPAP and AutoSet flow generators to humidify and heat the air delivered to the patient, helping to prevent the drying of nasal passages that can cause discomfort. Other optional accessories include cold passover humidifiers, carry bags and breathing circuits. The Company�� data/patient management products include S9 Embletta Adapter, ResScan v3.14, ResTraxx v17.1., ResTraxx v18.3, ResScan v3.16 and EasyCare 1.0.
The Company competes with Philips BV, DeVilbiss Healthcare., Fisher & Paykel Healthcare Corporation Limited, Apex Medical Corp, BMC Medical Co. Ltd and Weinmann Gerate fur Medizin GmbH + Co. KG.
Advisors' Opinion:- [By Ben Levisohn]
Resmed (RMD) has plunged 12% to $49.50 in after-hours trading after it reported a profit of 56 cents, below estimates of 58 cents.
Cliffs Natural Resources (CLF) has gained after it reported a profit of 68 cents, missing forecasts for 71 cents, but beat on revenue.
- [By Roberto Pedone]
Another earnings short-squeeze prospect is medical equipment player ResMed (RMD), which is set to release numbers on Wednesday after the market close. Wall Street analysts, on average, expect ResMed to report revenue of $400.01 million on earnings of 64 cents per share.
The current short interest as a percentage of the float for ResMed is extremely high at 25.6%. That means that out of the 139.26 million shares in the tradable float, 35.89 million shares are sold short by the bears. The bears have also been increasing their bets from the last reporting period by 5%, or by about 1.72 million shares. If the bears get caught pressing their bets into a bullish quarter, then shares of RMD could easily trend sharply higher post-earnings as the shorts rush to cover some of their positions.
From a technical perspective, RMD is currently trending above its 50-day moving average and just below its 200-day moving average, which is neutral trendwise. Shares of RMD have started to flirt with a near-term breakout trade today, since the stock has tested some past overhead resistance at $48.07 a share. That move is starting to push shares of RMD within range of triggering a much bigger breakout trade post-earnings.
If you're bullish on RMD, then I would wait until after its report and look for long-biased trades if this stock manages to break out above some key overhead resistance levels at $51.22 to $51.32 share with high volume. Look for volume on that move that hits near or above its three-month average action of 1.17 million shares. If that breakout hits post-earnings, then RMD will set up to re-fill some of its previous gap-down-day zone from October of 2013 that started just above $56 a share. If that gap gets filled with strong upside volume flows, then RMD could easily trend north of $60 a share.
I would simply avoid RMD or look for short-biased trades if after earnings
- [By Damian Illia]
A Delaware corporation formed in 1994, ResMed Inc. (RMD) is a global leading designer, developer, manufacturer and marketer of medical products for the diagnosis, treatment and management of sleep-disordered breathing (SDB) and other respiratory disorders. For the quarter ended in Dec. 31, 2013 ResMed reported a 2 percent increase (a 1 percent increase in constant currency basis) in revenue over the quarter ended in Dec. 31, 2012. However, these earnings failed to meet analyst estimates; and not without a reason. A relatively poor performance was expected due to continued pressure in the United States, especially as a consequence of the market's restructuring due to competitive Medicare bidding. This might also be one of the reasons why this stock still remains undervalued.
Best Gas Utility Companies To Own For 2014: Science Applications International Corp (SAIC)
Science Applications International Corporation, formerly SAIC Gemini, Inc., incorporated on February 1, 2013, is a scientific, engineering, and technology applications company. The Company uses its domain knowledge to solve problems in national security, energy and the environment, critical infrastructure, and health. The Company serves customers in the United States Department of Defense, the intelligence community, the United States Department of Homeland Security, other United States Government civil agencies and selected commercial markets. The Company provides services in two segments: government segment and commercial segment. Its government segment provides an array of technical services and solutions, primarily to United States federal, state and local government agencies and foreign governments. Its commercial segment provides technology-driven consulting, systems integration and outsourcing services and solutions in selected commercial markets.
Services
The Company provides systems development, technical and consulting services to federal, state, local law enforcement and criminal justice agencies, further promoting efficiency and effectiveness in preventing and controlling crime through systems, such as CODIS and LEO. The Company safeguards business-critical information, systems, and Websites with information security assessments and public key infrastructure solutions. The Company simplifies access to government goods and services through pre-negotiated federal contract vehicles. It provides government, commercial, and international clients with solutions to complex financial and resource problems. The Company provides geospatial products, services, and solutions for several industries, including agriculture, utility and defense. It provides a comprehensive portfolio of technology and domain specific solutions to its federal, state and local government and commercial health customers.
The Company helps companies to y operate, maintain, and manage wid! ely dispersed assets through consulting, enterprise asset management (EAM), help desk services and network services. The Company supports all phases for drug development: discovery, pre-clinical and clinical development and operations and compliance. It develops technologies, engineer solutions and provide analytical systems for maritime markets. It helps organizations improve product quality, more accurately determine product development or production schedule/cost, and increase productivity. The Company helps National Aeronautics and Space Administration (NASA) and the military, space and intelligence communities transition to faster, better and cheaper business processes through applied research & technology; information systems, and modeling and simulation. The Company offers corporate and individual training services ranging from elearning to training evaluation.
Aviation
The Company supports commercial and government customers with the latest aviation technology products. The Company�� products include Model 3800 Autopilot, FODetect , AeroPlanner, Memory Unit Tactical Air Crew Training System (MUTACTS), and SAIC Mission Planning System (MPS). The Model 3800 Autopilot is designed for installation in high-performance jet and turboprop aircraft but will function well in a range of fixed-wing aircraft. FODetect is an automated system that provides continuous monitoring with high-resolution and high-speed detection of foreign object debris (FOD) on critical aircraft operating areas. AeroPlanner provides a common tactical picture between control and combat systems by accessing parallel data from naval tactical data systems and retransmitting serially into multiple formats. SAIC's MUTACTS provides quick, accurate and post-flight review and analysis of military aircraft training missions. SAIC MPS consists of a line of simple to use computerized aircraft mission planning systems available for aircraft around the world.
Geospatial Products
The Company o! ffers a f! amily of geospatial solutions to support and gather GIS information for defense, intelligence and commercial customers. Its products include AeroPlanner.com, GRGlobe, GeoRover Software Products, ike 504, Percept, and WebCentric Geospatial Collaboration. AeroPlanner.com is a comprehensive flight-planning application for pilots of all levels. The GRGlobe desktop application brings core GIS functionality to a three dimensional (3D) globe environment providing the ability to create, edit, and visualize GIS data natively while supporting multiple formats such, as KML, shapefile and geodatabase. GeoRover geospatial software products are designed and sold as extensions of plug-in to the ArcMap component of Esri ArcGIS software versions 8.x and 9.x. The ike 504 is a handheld, GIS-related device that provides operators with methods to collect geospatial information on a target, including GPS coordinates and a photograph from a position up to 1,000 meters (3,280 feet) away. The SAIC Percept suite connects essential business information with real-world infrastructure and properties data. WebCentric Geospatial Collaboration is a Web-based, commercial-off-the-shelf geospatial presentation tool providing to dimensional (2D), 3D, and four dimensional (4D) views.
Ocean and Marine Systems
The Company develops marine products. These products monitor global climate change and marine meteorology, chart and analyze hydrographic data, and help to manage waste and control pollution. iTs products include COBIA Buoy, SAIC Tsunami Buoy (STB) Systems, ISS-2000, Survey Analysis and area Based EditoR (SABER), Incident Command Tool for Drinking Water Protection (ICWater), Plastics Waste Processor (PWP), Compress Melt Unit (CMU) Mod 0, Compress Melt Unit (CMU) Mod 1: Plastics Waste Processor, Large and Small Pulpers, Large and Small Pulpers, 10 GPM Oily Waste Polishing Unit, Topside and Dockside Chlorinators, and Ship Dechlorinator. COBIA Buoy is designed as a modular and fully reconfigurable buoy platform b! ased on t! echnologically advanced maritime expertise. SAIC Tsunami Buoy (STB) Systems are an enhanced version of the buoy system in use by the National Oceanic and Atmospheric Administration's DART detection system. The ISS-2000 Integrated Survey System was designed for professional hydrographers and surveyors and supports a range of high-performance, shallow-water survey operations. SABER is a tool for processing, editing, updating, viewing and analyzing hydrographic survey data. ICWater is designed to model drinking water contamination in real-time for a rapid, effective emergency response.
Rugged Hardware
The Company�� rugged hardware provides a range of commercial off-the-shelf equipment, as well as specialized custom-designed solutions, for installation into harsh tactical and industrial environments. Its products include Quicklock Cargo Restraint System, Passive LINK Tap (PLT), 1RU 8 Circuit Rugged Power Distribution Assembly (PDA), 1RU Fixed Expansion Chassis, 2RU Rugged cPCI Chassis High-Security Firewall System, Rugged Large liquid-crystal display (LCD) Color Flat Panel Displays (FPDs), Rugged Small LCD FPDs, Neptune 2 Rack Unit Workstation Consoles, and Rugged TigerShark Workstation Consoles. PLT provides a common tactical picture between control and combat systems by accessing parallel data from naval tactical data systems and retransmitting serially into multiple formats. The Quicklock Cargo Restraint System allows for secure tie-down of almost any cargo shape and is designed to prevent damage to and loss of equipment while in transit.
Safety and Security
The Company offers a variety of products to enhance safety and security in transportation, military, emergency response and other applications. Its product includes VACIS Cargo and Vehicle Inspection Systems, VACIS IP6500 FullScan Integrated Inspection System, VACIS XPL Passenger Vehicle Scanning System, and All-Terrain VACIS Imaging System. The Company�� VACIS systems scan cargo containers, tru! cks, cars! and other vehicles to help authorities search for weapons, nuclear material, narcotics, undeclared goods and other contraband at cargo terminals, border crossings, military facilities and other checkpoints. The VACIS IP6500 system safely scans occupied trucks and other vehicles of all sizes. The VACIS XPL system safely scans occupied cars and and other light vehicles.
Simulation
The Company provides a range of simulation products using in system engineering, software engineering, component engineering, signal and image processing, and custom system integration. Its products include OLIVE: On-Line Interactive Virtual Environment, RADSIM Radar Simulation 3.0, Reconfigurable Tactical Operations Simulator (RTOS), Non-Rated Crew Member Manned Module (NCM3), RC-12X Cockpit Procedural Trainer (CPT), Common Driver Trainer (CDT) Product Line, Combat Training Center-Instrumentation Systems (CTC-IS), STK/Missile Modeling Tools (STK/MMT), Tactical Engagement Simulation (TES) Systems, Common Vehicle System (CVS) Kit, CVS Abrams Adapter Kit, CVS Bradley Adapter Kit, Wireless Independent Target System (WITS), MK-19 Simulator Player Unit, Wireless Individual Weapon System (W-IWS), Mini MILES, Air Defense Weapons Systems (ADWS) MILES Kits, and Aviation Tactical Engagement Simulation System (AV-TESS). The Aviation Tactical Engagement Simulation System (AV-TESS) provides a flexible, training solution, tracking and weapons simulation system, and supports live force-on-force and force-on-target training and the evaluation and testing of new air vehicles and weapons systems. The Wireless Independent Target System (WITS) provides noncombat vehicles and targets, such as trucks, bridges and buildings, with a high-fidelity detection system for real-time casualty assessment.
Software
The Company is an SEI Partner for the Capability Maturity Model Integration (CMMI) project, a collaborative effort to provide models for achieving product and process improvement. Its products inc! lude Voic! e Identity Biometric Services (VIBES), Scale2Insight, Secure Multi-Tenancy, Advanced Analytics Suite, TeraText Database System, SIAM, Antfarm, EMTOOLS, MICHELLE, Enterprise Energy Dashboard, GeoRover Software Products, GeoViz- WebCentric GeoSpatial Collaboration, ISS-2000, Survey Analysis and area Based EditoR (SABER), AIMES, ISRCrossCue, RAVE, Omnifluent Suite of Human Language Technology Products, Flexible Tax Manager, SCOPTIMA Supply Chain Software, and Supply Operations Control System (SOCS). The Supply Operations Control System (SOCS) is a personal computer (PC) based inventory management system, and provides asset visibility, inventory control and supply support. SCOPTIMA Supply Chain Software is a secure, Web-enabled inventory system planner that provides demand forecasting to support efficient management and replenishment of large inventories of spare parts for aircraft and other platforms.
Transportation Products
The Company�� transportation systems helps companies and government agencies around the world improve efficiency, enhance safety and security, reduce errors and cut costs. Its products include Integrated Container Information System (ICIS), Intelligent Intermodal Solutions (IIS), Gatestand Driver Kiosk, CraneView Crane-Mounted OCR System, RailView Digital Video Recording System for Locomotives, and Transportation Visibility and Metrics System (TransVM). The RailView system continuously records digital video and key events as the locomotive travels, providing a reliable record for analysis of rail incidents. The CraneView system automatically identifies containers and records stow positions as the containers are moved by quay cranes in real time.
Advisors' Opinion:- [By John Reese]
Indeed, in 2013, the Greenblatt-based portfolio has bounced back strong, returning more than 50%. Below is a look at its current holdings.
EBIX, Inc. (EBIX)
Western Refining (WNR)
DirecTV (DTV)
ITT Educational Services (ESI)
Science Applications International (SAIC)
Weight Watchers International (WTW)
ConocoPhillips (COP)
AmSurg Corp. (AMSG)
PDL BioPharma (PDLI)
AFC Enterprises (AFCE)
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